Description

(S)-1-n-Boc-2-Methyl Piperazine-Hcl is a high-purity, chiral piperazine derivative used as a critical building block in advanced organic synthesis. This compound matters for its role in constructing complex molecular architectures with defined stereochemistry, which is essential for developing active pharmaceutical ingredients (APIs) and other fine chemicals. It is needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable, high-quality intermediates for their synthetic routes.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel drug candidates, particularly for central nervous system (CNS) and antiviral therapies.
• API Synthesis: Used in the construction of active pharmaceutical ingredients (APIs) where the (S)-configured 2-methyl piperazine moiety is required for biological activity.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Agrochemical Research: Employed in the synthesis of advanced, stereochemically defined agrochemicals and plant protection agents.
• Peptidomimetics: A valuable building block for creating peptidomimetic compounds in medicinal chemistry programs.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity chiral intermediates.

Basic Information

Product Name	(S)-1-n-Boc-2-Methyl Piperazine-Hcl
CAS No.	960283-58-3
Molecular Formula	C10H21ClN2O2
Molecular Weight	236.74 g/mol
Synonyms	(S)-1-(tert-Butoxycarbonyl)-2-methylpiperazine hydrochloride; (S)-1-Boc-2-methylpiperazine hydrochloride; (S)-2-Methyl-1-(tert-butoxycarbonyl)piperazine hydrochloride; (S)-N-Boc-2-methylpiperazine HCl; (S)-1-tert-Butyl 2-methylpiperazine-1-carboxylate hydrochloride; (S)-1-(Boc)-2-methylpiperazine hydrochloride; (S)-2-Methylpiperazine-1-carboxylic acid tert-butyl ester hydrochloride
EINECS	Contact for details

Quality Control

Our (S)-1-n-Boc-2-Methyl Piperazine-Hcl is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot undergoes comprehensive analytical testing, including chiral purity verification by HPLC. Certificates of Analysis (COA) detailing specific results for identity, purity, and related substances are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.