Description

4-(8-((4-(4-(tert-Butyl)Piperazin-1-Yl)Phenyl)Amino)-[1,2,4]Triazolo[1,5-A]Pyrazin-5-Yl)Furan-2-Carboxamide is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is valued for its role as a key building block in the research and development of novel therapeutic agents, particularly in oncology and targeted disease pathways. It is essential for pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in synthesizing next-generation active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of investigational new drugs, especially kinase inhibitors.
• Oncology Research: Serves as a core scaffold for developing targeted cancer therapies in preclinical and discovery phases.
• Biochemical Research: Used as a reference standard or a probe compound in biochemical assays and mechanism-of-action studies.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to optimize drug potency and selectivity.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP conditions.
• Academic Research: Utilized in university and institutional labs for cutting-edge chemical biology and drug discovery programs.

Basic Information

Item	Detail
Product Name	4-(8-((4-(4-(tert-Butyl)Piperazin-1-Yl)Phenyl)Amino)-[1,2,4]Triazolo[1,5-A]Pyrazin-5-Yl)Furan-2-Carboxamide
CAS No.	959754-85-9
Molecular Formula	C26H30N8O2
Molecular Weight	486.57 g/mol
Synonyms	4-(8-((4-(4-(tert-Butyl)piperazin-1-yl)phenyl)amino)-[1,2,4]triazolo[1,5-a]pyrazin-5-yl)furan-2-carboxamide; 959754-85-9; 4-[8-[[4-[4-(tert-butyl)piperazin-1-yl]phenyl]amino]-[1,2,4]triazolo[1,5-a]pyrazin-5-yl]furan-2-carboxamide; [1,2,4]Triazolo[1,5-a]pyrazine-5-carboxamide, 4-[8-[[4-[4-(1,1-dimethylethyl)-1-piperazinyl]phenyl]amino]-[1,2,4]triazolo[1,5-a]pyrazin-5-yl]-2-furanyl-; BDBM50164995; AKOS025147192; ZINC19764280; CHEMBL3186661
EINECS	Contact for details

Quality Control

Our 4-(8-((4-(4-(tert-Butyl)Piperazin-1-Yl)Phenyl)Amino)-[1,2,4]Triazolo[1,5-A]Pyrazin-5-Yl)Furan-2-Carboxamide is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment, supporting compliance with research and cGMP standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (HPLC)	Retention time corresponds to reference standard
Identification (NMR)	Spectrum consistent with structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.