Description

(3S)-4-Boc-1-Carboxymethyl-3-Methyl-Piperazin-2-One is a high-purity, advanced pharmaceutical intermediate featuring a protected piperazinone core structure. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), particularly in the development of protease inhibitors and other small-molecule therapeutics. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in drug discovery and process chemistry.

Application

• Key Intermediate in API Synthesis: Serves as a crucial building block for the production of protease inhibitor drugs, including treatments for viral infections like HIV and HCV.
• Peptidomimetic Research: Used in medicinal chemistry for designing and synthesizing novel peptidomimetic compounds to improve metabolic stability and bioavailability.
• Pharmaceutical Process Development: Employed in route scouting and scale-up activities for the commercial manufacturing of target drug molecules.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global pharmaceutical market.
• Academic & Industrial R&D: Facilitates exploratory research in organic and medicinal chemistry for novel therapeutic targets.

Basic Information

Product Name	(3S)-4-Boc-1-Carboxymethyl-3-Methyl-Piperazin-2-One
CAS No.	959571-65-4
Molecular Formula	C13H22N2O5
Molecular Weight	286.33 g/mol
Synonyms	1-[(tert-Butoxycarbonyl)methyl]-3-methyl-2-oxopiperazine-4-carboxylic acid; 4-[(tert-Butoxycarbonyl)amino]-1-(carboxymethyl)-3-methyl-2-piperazinone; (3S)-1-Carboxymethyl-4-(tert-butoxycarbonyl)-3-methylpiperazin-2-one; Boc-Pip(Me,COOH)-OH; tert-Butyl (3S)-1-carboxymethyl-3-methyl-2-oxopiperazine-4-carboxylate; 959571-65-4; (S)-4-Boc-1-Carboxymethyl-3-Methyl-2-Piperazinone
EINECS	Contact for details

Quality Control

Our (3S)-4-Boc-1-Carboxymethyl-3-Methyl-Piperazin-2-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, supporting compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under a dry atmosphere to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH limits

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.