Description

Phosphoramidic Difluoride, n-[(Trimethylsilyl)oxy]- is a specialized organosilicon reagent containing both phosphoramidic difluoride and trimethylsilyloxy functional groups. This compound is valued for its role as a key intermediate in the synthesis of complex organophosphorus molecules and as a versatile silylating agent in advanced organic chemistry. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those containing phosphorus-based functional groups.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides, herbicides, and plant growth regulators.
• Silylation Reagent: Functions as a protecting group agent for alcohols and other protic functional groups in multi-step synthetic sequences.
• Organophosphorus Chemistry Research: Serves as a precursor for developing new ligands, catalysts, and flame retardants in academic and industrial R&D laboratories.
• Material Science Precursor: Employed in the creation of specialty polymers and advanced materials with tailored surface properties.
• Process Chemistry: Utilized in scale-up and optimization studies for the commercial production of high-value chemical products.

Basic Information

Product Name	Phosphoramidic Difluoride, n-[(Trimethylsilyl)oxy]-
CAS No.	959272-09-4
Molecular Formula	C3H10F2NO2PSi
Molecular Weight	197.18 g/mol
Synonyms	N-(Trimethylsilyloxy)phosphoramidic difluoride; Phosphoramidic difluoride, N-(trimethylsilyl) ester; (Trimethylsilyloxy)phosphoramidic difluoride; O-Trimethylsilyl phosphoramidofluoridate; TMSOPF; N-(Trimethylsiloxy)phosphoramidic difluoride; Phosphoramidofluoridic acid, N-(trimethylsilyl) ester
EINECS	Contact for details

Quality Control

Our Phosphoramidic Difluoride, n-[(Trimethylsilyl)oxy]- is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is analyzed using advanced chromatographic and spectroscopic techniques. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening. Keep away from strong bases and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.