Description

(Acetylmethylene)Triphenylphosphorane is a versatile and highly reactive Wittig reagent, a key organophosphorus compound in synthetic organic chemistry. Its primary value lies in its ability to facilitate the efficient synthesis of alkenes from carbonyl compounds, offering excellent stereoselectivity under mild conditions. This reagent is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors, enabling the construction of complex molecular frameworks for active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate Synthesis: A crucial reagent for constructing carbon-carbon double bonds in the synthesis of complex drug molecules and bioactive compounds.
• Agrochemical Production: Used in the manufacture of pesticides, herbicides, and plant growth regulators requiring specific alkene functionalities.
• Material Science Research: Employed in the synthesis of organic semiconductors, liquid crystals, and polymers with tailored optical or electronic properties.
• Fine Chemical Synthesis: Facilitates the production of flavors, fragrances, and specialty chemicals where precise olefination is required.
• Academic & R&D Laboratories: A staple reagent for methodology development and exploratory synthesis in organic chemistry.
• Olefination Reactions: Specifically for the conversion of aldehydes and ketones into substituted alkenes (Wittig reaction).

Basic Information

Product Name	(Acetylmethylene)Triphenylphosphorane
CAS No.	1439-36-7
Molecular Formula	C21H19OP
Molecular Weight	318.35 g/mol
Synonyms	Acetylmethylenetriphenylphosphorane; (Acetyl methylene) triphenylphosphorane; (Acetyl methylene) triphenyl phosphorane; Acetylmethylene(triphenyl)phosphorane; (Acetylmethylene)triphenyl-λ5-phosphane; Triphenyl(1-oxoethylidene)phosphorane; 2-Oxopropylidenetriphenylphosphorane; Wittig reagent (acetyl methylene)
EINECS	215-873-9

Quality Control

Our (Acetylmethylene)Triphenylphosphorane is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including NMR, HPLC, and titration methods, to ensure high chemical purity and consistent performance. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with specified parameters. We support cGMP and ISO standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent decomposition.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.