Description

2-Bromo-5-(Piperidin-4-Ol)Pyrazine is a high-purity, heterocyclic organic building block of significant interest in advanced chemical synthesis. This compound matters as a versatile and critical intermediate for constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily needed by medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Medicinal Chemistry: Used in structure-activity relationship (SAR) studies and for introducing the piperidin-ol moiety into lead compounds to modulate solubility and biological activity.
• Agrochemical Synthesis: Serves as a building block for developing novel herbicides, fungicides, and insecticides with specific modes of action.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes for studying enzyme function and biological pathways.
• Ligand Development: Acts as a precursor for creating complex ligands used in catalysis and material science.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research organizations for custom synthesis projects and scale-up activities.

Basic Information

Product Name	2-Bromo-5-(Piperidin-4-Ol)Pyrazine
CAS No.	959239-22-6
Molecular Formula	C9H12BrN3O
Molecular Weight	258.12 g/mol
Synonyms	2-Bromo-5-(4-hydroxypiperidin-1-yl)pyrazine; 4-(6-Bromopyrazin-2-yl)piperidin-4-ol; 1-(6-Bromo-2-pyrazinyl)-4-piperidinol; Piperidin-4-ol, 1-(6-bromo-2-pyrazinyl)-; 959239-22-6; 2-Bromo-5-(4-hydroxy-1-piperidinyl)pyrazine
EINECS	Contact for details

Quality Control

Our 2-Bromo-5-(Piperidin-4-Ol)Pyrazine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.