Description

2-Bromo-5-isopropoxypyrazine is a high-purity brominated pyrazine derivative, a key synthetic intermediate valued for its reactivity and structural versatility. This compound is essential for constructing complex molecular architectures in advanced research and development. It is primarily utilized by pharmaceutical, agrochemical, and specialty chemical manufacturers for applications in drug discovery, crop protection, and materials science.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other heterocyclic drug candidates.
• Agrochemical Synthesis: Used in the research and development of novel pesticides, herbicides, and fungicides, leveraging the pyrazine core for biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organometallic catalysts used in cross-coupling reactions and other catalytic processes.
• Material Science Research: Employed in the development of organic electronic materials, such as semiconductors and light-emitting components, due to its electron-deficient aromatic system.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and enzyme functions.
• Custom Synthesis and Contract Manufacturing: A key starting material for custom synthesis projects and scale-up production under cGMP or ISO standards for client-specific molecules.

Basic Information

Product Name	2-Bromo-5-isopropoxypyrazine
CAS No.	959238-74-5
Molecular Formula	C7H9BrN2O
Molecular Weight	217.06 g/mol
Synonyms	5-Isopropoxy-2-bromopyrazine; 2-Bromo-5-(1-methylethoxy)pyrazine; Pyrazine, 2-bromo-5-(1-methylethoxy)-; 2-Bromo-5-(propan-2-yloxy)pyrazine; 959238-74-5; 2-Br-5-iPrO-Pyrazine
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-5-isopropoxypyrazine is produced and tested under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive synthetic applications. A detailed Certificate of Analysis (COA), including results from HPLC, NMR, and GC-MS, is supplied with each shipment to guarantee identity, purity, and consistency for your R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed and under an inert atmosphere for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.