Description

2-(4-Boc-Piperazino)-2-(4-Pyridyl)Acetic Acid Methyl Ester is a high-purity, advanced pharmaceutical intermediate featuring a protected piperazine and pyridyl acetic acid ester structure. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), particularly in medicinal chemistry research and development. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the production of novel therapeutics, where its specific functional groups serve as key building blocks.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of novel drug candidates, particularly those targeting neurological and oncological pathways.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new chemical entities with improved efficacy and safety profiles.
• API Synthesis: Serves as a precursor in the production of complex Active Pharmaceutical Ingredients (APIs) that incorporate piperazine and pyridine pharmacophores.
• Custom Synthesis & Contract Manufacturing: Employed by CDMOs (Contract Development and Manufacturing Organizations) for the cGMP production of clinical trial materials and commercial APIs.
• Protease Inhibitor Development: Potential use in the synthesis of compounds designed to inhibit specific enzymes, such as those involved in viral replication or cellular signaling.
• Chemical Biology & Probe Development: Utilized in the creation of molecular probes for studying biological systems and target identification.

Basic Information

Product Name	2-(4-Boc-Piperazino)-2-(4-Pyridyl)Acetic Acid Methyl Ester
CAS No.	957761-38-5
Molecular Formula	C17H25N3O4
Molecular Weight	335.40 g/mol
Synonyms	Methyl 2-(4-((tert-butoxycarbonyl)amino)piperazin-1-yl)-2-(pyridin-4-yl)acetate; 2-(4-Boc-Piperazino)-2-(4-Pyridyl)Acetic Acid Methyl Ester; 2-(4-(tert-Butoxycarbonyl)piperazin-1-yl)-2-(pyridin-4-yl)acetic acid methyl ester; 1-Boc-4-(1-Methoxy-1-oxo-2-(pyridin-4-yl)ethyl)piperazine; tert-Butyl 4-(1-methoxy-1-oxo-2-(pyridin-4-yl)ethyl)piperazine-1-carboxylate; 957761-38-5; Boc-Pip-Pyridyl-Gly-OMe
EINECS	Contact for details

Quality Control

Our 2-(4-Boc-Piperazino)-2-(4-Pyridyl)Acetic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing including HPLC, NMR, and mass spectrometry to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing all specified parameters. We support development and commercial projects with material suitable for research use and can supply grades aligned with cGMP guidelines for advanced pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to minimize exposure to atmospheric humidity. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.