Description

3,6-Dibromopyrazin-2-Amine is a high-purity, halogenated pyrazine derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its reactivity, particularly in cross-coupling reactions and as a precursor for complex heterocyclic systems. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Building block for creating novel herbicides, fungicides, and insecticides with enhanced efficacy.
• Material Science Research: Used in the development of organic semiconductors, ligands for catalysis, and photoactive materials.
• Cross-Coupling Reactions: Serves as a versatile substrate for Suzuki, Buchwald-Hartwig, and other palladium-catalyzed coupling reactions to form complex biaryl structures.
• Chemical Library Development: A valuable scaffold for medicinal chemistry and high-throughput screening to discover new bioactive compounds.
• Academic & Industrial R&D: Fundamental reagent for methodological studies in organic chemistry and process development.

Basic Information

Product Name	3,6-Dibromopyrazin-2-Amine
CAS No.	957230-70-5
Molecular Formula	C4H3Br2N3
Molecular Weight	252.89 g/mol
Synonyms	2-Amino-3,6-dibromopyrazine; 3,6-Dibromo-2-pyrazinamine; 3,6-Dibromopyrazin-2-ylamine; 2-Pyrazinamine, 3,6-dibromo-; 957230-70-5; 3,6-Dibromo-2-aminopyrazine
EINECS	Contact for details

Quality Control

Our 3,6-Dibromopyrazin-2-Amine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our commitment to cGMP principles and rigorous in-process controls guarantees a reliable supply of this high-value intermediate for your most demanding applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.