Description

3,6-Dibromopyrazine-2-Carboxylic Acid is a high-value, multi-functional heterocyclic building block essential for advanced organic synthesis. Its core value lies in the strategic positioning of bromine atoms and a carboxylic acid group on the pyrazine ring, enabling precise derivatization and the construction of complex molecular architectures. This compound is critically needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used to construct novel pyrazine-based herbicides, fungicides, and insecticides with enhanced efficacy.
• Ligand & Catalyst Development: Serves as a versatile scaffold for creating specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Material Science Building Block: Employed in the development of organic semiconductors, conductive polymers, and advanced electronic materials.
• Cross-Coupling Reactions: The bromine substituents make it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions.
• Peptidomimetics & Bioisosteres: The pyrazine core can act as a bioisostere for benzene or pyridine rings in drug design, improving pharmacokinetic properties.

Basic Information

Product Name	3,6-Dibromopyrazine-2-Carboxylic Acid
CAS No.	957230-68-1
Molecular Formula	C5H2Br2N2O2
Molecular Weight	281.89 g/mol
Synonyms	2,5-Dibromopyrazine-6-carboxylic acid; 3,6-Dibromo-2-pyrazinecarboxylic acid; 2-Pyrazinecarboxylic acid, 3,6-dibromo-; DBPC Acid
EINECS	Contact for details

Quality Control

Our 3,6-Dibromopyrazine-2-Carboxylic Acid is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and scale-up. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable, and our quality protocols are designed to meet the stringent requirements of pharmaceutical and fine chemical industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥97.0%
Purity (HPLC, Area%)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.