Description

3,6,9,12-Tetraoxatetradecan-1-Ol, 14-Bromo- is a specialized brominated polyethylene glycol (PEG) derivative, a key intermediate in advanced organic synthesis. This compound matters for its unique bifunctional structure, combining a reactive bromoalkyl group with a hydrophilic PEG-like chain, enabling precise chemical modifications and conjugation. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and materials science sectors who require a reliable building block for creating functionalized polymers, prodrugs, and cross-linking agents.

Application

• Pharmaceutical Intermediate: Used in the synthesis of prodrugs, drug-polymer conjugates, and targeted therapeutic agents to enhance solubility and bioavailability.
• Bioconjugation & Linker Chemistry: Serves as a heterobifunctional cross-linker or spacer arm for attaching molecules (e.g., dyes, peptides, proteins) to surfaces or other biomolecules.
• Polymer & Materials Science: A key monomer or functionalization agent for creating novel amphiphilic block copolymers, hydrogels, and surface-modifying coatings.
• Chemical Synthesis Building Block: The reactive bromine site allows for further nucleophilic substitution reactions (e.g., with amines, thiols) to introduce desired functionalities.
• Nanoparticle & Micelle Functionalization: Employed to modify the surface properties of nanoparticles, improving stability, biocompatibility, and targeting capabilities.
• Research & Development: A valuable tool in academic and industrial R&D for exploring new synthetic pathways and material properties.

Basic Information

Product Name	3,6,9,12-Tetraoxatetradecan-1-Ol, 14-Bromo-
CAS No.	957205-14-0
Molecular Formula	C10H21BrO5
Molecular Weight	301.18 g/mol
Synonyms	14-Bromo-3,6,9,12-tetraoxatetradecan-1-ol; 2-[2-[2-(2-Bromoethoxy)ethoxy]ethoxy]ethanol; Br-PEG4-OH; Bromo-PEG4-alcohol; 1-Bromo-3,6,9,12-tetraoxatetradecan-14-ol; 2,5,8,11-Tetraoxatridecan-13-ol, 1-bromo-; 14-Bromo-3,6,9,12-tetraoxatetradecane-1-ol; Bromo tetraethylene glycol
EINECS	Contact for details

Quality Control

Our 3,6,9,12-Tetraoxatetradecan-1-Ol, 14-Bromo- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC, to ensure high purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Bromine Content	Conforms to theoretical

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.