Description

[1,2,4]Triazolo[4,3-A]Quinoline, 8-Methoxy-5-Methyl-1-[[[4-(1H-Pyrazol-1-Yl)Phenyl]Methyl]Thio]- is a sophisticated heterocyclic compound that serves as a key advanced intermediate in modern synthetic chemistry. Its complex fused-ring structure, incorporating triazoloquinoline and pyrazole moieties, makes it a high-value building block for the development of novel active molecules. This compound is primarily sought by pharmaceutical R&D and agrochemical research organizations for the synthesis of new drug candidates and specialty chemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of potential therapeutic agents, particularly for central nervous system (CNS) targets, kinase inhibitors, and anti-infective drugs.
• Agrochemical Research: Used in the development of novel pesticides, herbicides, and fungicides due to its bioactive heterocyclic scaffold.
• Organic Synthesis Building Block: Employed in medicinal and combinatorial chemistry for constructing complex molecular libraries for high-throughput screening.
• Material Science Research: Investigated as a precursor for organic electronic materials, such as OLEDs or charge-transport layers, owing to its conjugated system.
• Biochemical Probe Development: Serves as a core structure for designing fluorescent probes or enzyme inhibitors for biochemical assays.
• Academic & Contract Research: Utilized in universities and CROs for fundamental research in heterocyclic chemistry and reaction methodology development.

Basic Information

Item	Details
Product Name	[1,2,4]Triazolo[4,3-A]Quinoline, 8-Methoxy-5-Methyl-1-[[[4-(1H-Pyrazol-1-Yl)Phenyl]Methyl]Thio]-
CAS No.	956768-66-4
Molecular Formula	C22H19N5OS
Molecular Weight	401.48 g/mol
Synonyms	8-Methoxy-5-methyl-1-({[4-(1H-pyrazol-1-yl)phenyl]methyl}sulfanyl)[1,2,4]triazolo[4,3-a]quinoline; 1-[[[4-(1H-Pyrazol-1-yl)phenyl]methyl]thio]-8-methoxy-5-methyl-[1,2,4]triazolo[4,3-a]quinoline; [1,2,4]Triazolo[4,3-a]quinoline, 8-methoxy-5-methyl-1-[[[4-(1H-pyrazol-1-yl)phenyl]methyl]thio]-; CAS 956768-66-4
EINECS	Contact for details

Quality Control

Our production of [1,2,4]Triazolo[4,3-A]Quinoline, 8-Methoxy-5-Methyl-1-[[[4-(1H-Pyrazol-1-Yl)Phenyl]Methyl]Thio]- adheres to a strict quality management system. Every batch undergoes comprehensive analytical characterization using techniques such as HPLC, NMR, and MS to confirm identity and purity. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting critical parameters including assay, related substances, and residual solvents. We support cGMP compliance for pharmaceutical applications and can tailor specifications to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.