Description

Urea, n-[3-[(2,3-Dihydro-2-Oxo-1H-Imidazo[4,5-B]Pyridin-7-Yl)Oxy]Phenyl]-N'-[3-(1,1-Dimethylethyl)-1-(4-Methylphenyl)-1H-Pyrazol-5-Yl]- is a high-purity, complex heterocyclic urea derivative designed for advanced research and development. This compound serves as a critical pharmacological reference standard and a key building block in the synthesis of novel therapeutic agents. It is primarily utilized by pharmaceutical R&D teams and contract research organizations (CROs) focused on discovering new small molecule drugs.

Application

• Pharmaceutical Research & Development: Acts as a key intermediate or reference standard in the synthesis and screening of novel drug candidates.
• Kinase Inhibitor Development: Serves as a core scaffold for designing and optimizing potent and selective kinase inhibitors due to its imidazopyridine and pyrazole motifs.
• Medicinal Chemistry: Used in structure-activity relationship (SAR) studies to explore biological activity and improve drug-like properties.
• Biochemical Assays: Employed as a standard or inhibitor in high-throughput screening (HTS) campaigns to identify hits for various disease targets.
• Contract Manufacturing: Supplied as a high-purity building block for custom synthesis and scale-up processes under cGMP conditions.
• Academic Research: Utilized in university and institutional labs for fundamental studies in chemical biology and drug discovery mechanisms.

Basic Information

Product Name	Urea, n-[3-[(2,3-Dihydro-2-Oxo-1H-Imidazo[4,5-B]Pyridin-7-Yl)Oxy]Phenyl]-N'-[3-(1,1-Dimethylethyl)-1-(4-Methylphenyl)-1H-Pyrazol-5-Yl]-
CAS No.	956488-03-2
Molecular Formula	C28H27N7O3
Molecular Weight	509.56 g/mol
Synonyms	N-[3-[(2,3-Dihydro-2-oxo-1H-imidazo[4,5-b]pyridin-7-yl)oxy]phenyl]-N'-[3-(tert-butyl)-1-(p-tolyl)-1H-pyrazol-5-yl]urea; 7-[3-[[[3-(1-tert-Butyl-5-p-tolyl-1H-pyrazol-3-yl)amino]carbonyl]amino]phenoxy]-1H-imidazo[4,5-b]pyridin-2(3H)-one; UNII-0J3C2R6Q5I; 0J3C2R6Q5I; BDBM50157857; HY-101966; AOB83707; CHEMBL3185222
EINECS	Contact for details

Quality Control

Our Urea, n-[3-[(2,3-Dihydro-2-Oxo-1H-Imidazo[4,5-B]Pyridin-7-Yl)Oxy]Phenyl]-N'-[3-(1,1-Dimethylethyl)-1-(4-Methylphenyl)-1H-Pyrazol-5-Yl]- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical characterization, including HPLC purity analysis, mass spectrometry (MS), and nuclear magnetic resonance (NMR) to confirm identity and purity. A detailed Certificate of Analysis (COA) is provided with every shipment to ensure traceability and compliance with your research specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. The compound is light-sensitive (store away from light) and hygroscopic (moisture-sensitive). For long-term storage, consider desiccation or storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.