Description

(S)-3-Amino-1-Methylpiperidin-2-One Hydrochloride is a high-purity chiral building block and pharmaceutical intermediate of significant commercial importance. Its value lies in its role as a key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and other therapeutic areas. This compound is essential for research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in asymmetric synthesis and drug discovery programs.

Application

• Pharmaceutical Intermediate: A critical chiral precursor in the synthesis of complex drug molecules and novel APIs.
• Asymmetric Synthesis: Used as a building block for constructing enantiomerically pure compounds in medicinal chemistry.
• Neurological Research: Serves as a key component in the development of potential therapeutics targeting neurological disorders.
• Process Chemistry & Scale-up: Employed in route scouting, optimization, and commercial-scale manufacturing of pharmaceutical actives.
• Contract Research & Manufacturing: Supplied to CDMOs and CROs for client-specific custom synthesis projects.
• Chemical Reference Standard: Used as a high-purity standard for analytical method development and quality control.

Basic Information

Product Name	(S)-3-Amino-1-Methylpiperidin-2-One Hydrochloride
CAS No.	956109-56-1
Molecular Formula	C6H13N2O·HCl
Molecular Weight	164.64 g/mol (Free base: 128.18 g/mol)
Synonyms	(S)-3-Amino-1-methyl-2-piperidinone hydrochloride; (3S)-3-Amino-1-methylpiperidin-2-one hydrochloride; (S)-1-Methyl-3-amino-2-piperidinone HCl; (S)-3-Amino-1-methyl-2-piperidone hydrochloride; 2-Piperidinone, 3-amino-1-methyl-, hydrochloride, (3S)-; (S)-3-Amino-1-methylpiperidin-2-one HCl; (S)-1-Methyl-3-aminopiperidin-2-one hydrochloride
EINECS	Contact for details

Quality Control

Our (S)-3-Amino-1-Methylpiperidin-2-One Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the stringent requirements for pharmaceutical R&D and manufacturing. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert conditions (e.g., nitrogen atmosphere) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.