Description

1-Methylsulfonyl-2,2-Dimethylpiperazine Hydrochloride is a high-purity, functionalized piperazine derivative with a sulfonyl group, offered as a hydrochloride salt for enhanced stability and handling. This compound serves as a critical pharmaceutical intermediate and research chemical in the development of novel active ingredients. It is primarily utilized by R&D laboratories, process chemists, and manufacturers in the pharmaceutical and agrochemical sectors seeking to incorporate its unique structural motif into new molecular entities.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, particularly for central nervous system (CNS) and oncology targets.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its heterocyclic structure.
• Chemical Synthesis Reagent: Acts as a versatile precursor or reactant in organic synthesis for introducing the methylsulfonyl-piperazine moiety.
• Bioconjugation & Linker Chemistry: Potential use in creating specialized linkers for antibody-drug conjugates (ADCs) or proteolysis-targeting chimeras (PROTACs).
• Academic & Institutional Research: Employed in medicinal chemistry programs and pharmacological studies within universities and research institutes.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.

Basic Information

Product Name	1-Methylsulfonyl-2,2-Dimethylpiperazine Hydrochloride
CAS No.	956034-43-8
Molecular Formula	C7H17ClN2O2S
Molecular Weight	228.74 g/mol
Synonyms	2,2-Dimethyl-1-(methylsulfonyl)piperazine hydrochloride; 1-(Methylsulfonyl)-2,2-dimethylpiperazine hydrochloride; 2,2-Dimethylpiperazine-1-sulfonic acid methyl ester hydrochloride; N-(Methylsulfonyl)-2,2-dimethylpiperazine hydrochloride; Piperazine, 1-(methylsulfonyl)-2,2-dimethyl-, hydrochloride; 956034-43-8; 1-Methanesulfonyl-2,2-dimethylpiperazine HCl
EINECS	Contact for details

Quality Control

Our 1-Methylsulfonyl-2,2-Dimethylpiperazine Hydrochloride is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications and test results are provided and available upon request, supporting compliance with cGMP and ICH guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.