Description

tert-Butyl 2-((Methylamino)Methyl)Pyrrolidine-1-Carboxylate is a protected pyrrolidine derivative that serves as a crucial chiral building block in advanced organic synthesis. Its value lies in providing a versatile scaffold for constructing complex molecules with defined stereochemistry, essential for developing active pharmaceutical ingredients (APIs). This intermediate is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel therapeutic agents and crop protection compounds.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the development of central nervous system (CNS) drugs, antiviral agents, and enzyme inhibitors.
• Agrochemical Synthesis: Building block for creating novel pesticides and herbicides with specific stereochemical activity.
• Asymmetric Catalysis: Used as a precursor for chiral ligands and organocatalysts in enantioselective synthesis.
• Peptidomimetic Research: Core structure for designing and synthesizing conformationally constrained peptide analogs.
• Chemical Biology Probes: Scaffold for developing molecular probes to study biological pathways and protein interactions.
• Custom Synthesis: Serves as a starting material for contract research organizations (CROs) and CDMOs for client-specific projects.

Basic Information

Product Name	tert-Butyl 2-((Methylamino)Methyl)Pyrrolidine-1-Carboxylate
CAS No.	955979-19-8
Molecular Formula	C12H24N2O2
Molecular Weight	228.33 g/mol
Synonyms	1-Boc-2-((Methylamino)Methyl)Pyrrolidine; 1-(tert-Butoxycarbonyl)-2-((Methylamino)Methyl)Pyrrolidine; tert-Butyl 2-[(Methylamino)Methyl]-1-pyrrolidinecarboxylate; 2-((Methylamino)Methyl)-1-pyrrolidinecarboxylic acid tert-butyl ester; N-Boc-2-(Methylaminomethyl)pyrrolidine; (S)-tert-Butyl 2-((Methylamino)Methyl)Pyrrolidine-1-Carboxylate (for enantiopure form); (R)-tert-Butyl 2-((Methylamino)Methyl)Pyrrolidine-1-Carboxylate (for enantiopure form)
EINECS	Contact for details

Quality Control

Our tert-Butyl 2-((Methylamino)Methyl)Pyrrolidine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (for enantiopure grades)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.