Description

(R)-1-Boc-2-Isopropyl-Piperazine Hydrochloride is a high-purity chiral piperazine derivative, a critical building block in modern pharmaceutical synthesis. This compound is valued for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs), particularly for chiral drugs targeting the central nervous system and other therapeutic areas. It is essential for research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in asymmetric synthesis and process chemistry.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the synthesis of complex drug molecules, particularly in the development of protease inhibitors, kinase inhibitors, and other targeted therapies.
• Asymmetric Synthesis: Used as a chiral auxiliary or a scaffold to introduce stereochemical complexity in medicinal chemistry and process research.
• API Development: Serves as a key building block in the research, development, and scale-up manufacturing of new Active Pharmaceutical Ingredients (APIs).
• Chemical Biology & Proteomics: Employed in the design and synthesis of molecular probes and tool compounds for studying biological pathways.
• Custom Synthesis & CDMO Projects: A fundamental starting material for contract research and manufacturing organizations specializing in custom chiral chemistry.

Basic Information

Product Name	(R)-1-Boc-2-Isopropyl-Piperazine Hydrochloride
CAS No.	955979-06-3
Molecular Formula	C12H25ClN2O2
Molecular Weight	264.79 g/mol
Synonyms	(R)-1-(tert-Butoxycarbonyl)-2-(propan-2-yl)piperazine hydrochloride; (R)-1-Boc-2-(1-Methylethyl)piperazine hydrochloride; (R)-N-Boc-2-Isopropylpiperazine hydrochloride; (R)-2-Isopropyl-1-(tert-butoxycarbonyl)piperazine hydrochloride; tert-Butyl (R)-2-isopropylpiperazine-1-carboxylate hydrochloride; (R)-1-Boc-2-isopropylpiperazine HCl; (R)-Boc-2-isopropylpiperazine hydrochloride
EINECS	Contact for details

Quality Control

Our (R)-1-Boc-2-Isopropyl-Piperazine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the stringent requirements for pharmaceutical R&D and cGMP manufacturing. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.