Description

4(E),7(Z),10(Z),13(Z),16(Z),19(Z)-Docosahexaenoic Acid is a specific, high-purity stereoisomer of the essential ω-3 fatty acid DHA, identified by CAS number 955920-48-6. This compound is critical for advanced research and development where precise molecular structure and biological activity are paramount. It is primarily sought by pharmaceutical, nutraceutical, and advanced biomedical research sectors for applications in lipidomics, drug discovery, and the formulation of specialized nutritional supplements.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for the identification, assay, and purity testing of DHA in active pharmaceutical ingredients (APIs) and finished drug products.
• Biomedical & Lipidomic Research: Serves as a critical reagent in studying the specific biological functions, metabolic pathways, and signaling roles of DHA stereoisomers in cellular and in vivo models.
• High-End Nutraceutical Development: Incorporated into premium-grade dietary supplements and functional foods where defined isomer content is linked to enhanced bioavailability and efficacy.
• Analytical Chemistry: Employed as an analytical standard for method development and validation in chromatographic techniques (HPLC, GC) for accurate quantification of DHA isomers in complex matrices.
• Cosmeceutical Formulations: Used in advanced skincare products targeting anti-inflammatory and skin barrier repair benefits due to its specific structural properties.

Basic Information

Product Name	4(E),7(Z),10(Z),13(Z),16(Z),19(Z)-Docosahexaenoic Acid
CAS No.	955920-48-6
Molecular Formula	C22H32O2
Molecular Weight	328.49 g/mol
Synonyms	(4E,7Z,10Z,13Z,16Z,19Z)-Docosa-4,7,10,13,16,19-hexaenoic Acid; all-cis-4,7,10,13,16,19-Docosahexaenoic Acid Isomer; DHA Isomer; cis-4,7,10,13,16,19-Docosahexaenoic Acid; 22:6(n-3) Isomer; MorDHA; Cervonic Acid Isomer
EINECS	Contact for details

Quality Control

Our 4(E),7(Z),10(Z),13(Z),16(Z),19(Z)-Docosahexaenoic Acid is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including chiral HPLC and GC-MS, to confirm stereochemical purity and identity. Certificates of Analysis (COA) detailing purity, isomer content, and impurity profiles are provided and can be tailored to meet specific pharmacopeial or internal specifications.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the container to reach room temperature in a desiccator before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	Colorless to pale yellow oil
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0% (Total Isomer Content)
Isomeric Purity (Chiral HPLC)	≥ 95.0% (4E,7Z,10Z,13Z,16Z,19Z isomer)
Peroxide Value	< 5.0 meq/kg
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.