Description

1,2-Distearoyl-Sn-Glycero-3-Phosphoethanolamine is a high-purity, synthetic phospholipid essential for creating stable and functional lipid-based delivery systems. Its primary value lies in its role as a key structural and functional component in liposomes and lipid nanoparticles, enabling the encapsulation and targeted delivery of sensitive active ingredients. This product is critically needed by researchers and manufacturers in the pharmaceutical, biotechnology, and advanced cosmetics industries for developing next-generation therapeutics and high-performance formulations.

Application

• Liposome Formulation: A fundamental building block for constructing stable liposomal vesicles for drug delivery.
• mRNA-LNP Therapeutics: Used as a helper lipid or structural component in lipid nanoparticle (LNP) systems for nucleic acid delivery, including mRNA vaccines and therapies.
• Biomimetic Membrane Research: Employed in model membrane studies to investigate lipid bilayer properties and protein-lipid interactions.
• Cosmetic Nanocarriers: Integral to creating nano-emulsions and other advanced delivery systems for active cosmetic ingredients (ACI) in skincare.
• Diagnostic Reagents: Used in the preparation of reagents and kits for clinical diagnostics and biochemical assays.
• Surface Modification: Applied for coating and functionalizing surfaces to create biocompatible interfaces in medical devices and sensors.

Basic Information

Product Name	1,2-Distearoyl-Sn-Glycero-3-Phosphoethanolamine
CAS No.	1069-79-0
Molecular Formula	C41H82NO8P
Molecular Weight	748.06 g/mol
Synonyms	DSPE; 1,2-Distearoylphosphatidylethanolamine; Distearoylphosphatidylethanolamine; DSPE Lipid; N-(1,2-Distearoyl-sn-glycero-3-phospho)ethanolamine; Phosphatidylethanolamine, 1,2-distearoyl-; PE(18:0/18:0); L-α-Phosphatidylethanolamine, 1,2-dihexadecanoyl-
EINECS	213-973-1

Quality Control

Our 1,2-Distearoyl-Sn-Glycero-3-Phosphoethanolamine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and GMP-grade applications. All products undergo rigorous analytical testing, including HPLC, TLC, and NMR, to confirm identity, purity, and the absence of critical impurities. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Due to its hygroscopic nature, the container must be sealed tightly after each use to minimize exposure to moisture. For long-term stability, avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Solvent Residues	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.