Description

1,2-Distearoyl-Rac-Glycerol is a high-purity synthetic glyceride, specifically a diacylglycerol (DAG) where the 1 and 2 positions of the glycerol backbone are esterified with stearic acid. This compound serves as a critical pharmaceutical intermediate and a versatile lipid excipient in advanced formulations. It is essential for manufacturers in the pharmaceutical, nutraceutical, and specialty chemical industries requiring a defined, high-quality lipid component for research, development, and production.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex lipids, phospholipids, and prodrugs.
• Lipid-Based Drug Delivery Systems: Used as a component in solid lipid nanoparticles (SLNs), nanoemulsions, and self-emulsifying drug delivery systems (SEDDS) to enhance drug solubility and bioavailability.
• Biochemical Research: Serves as a standard or substrate in enzymatic studies, particularly those involving lipases and phospholipases.
• Cosmetic Formulations: Acts as an emollient and texture enhancer in high-end skincare products.
• Food Science Research: Utilized as a model compound in studies of fat metabolism, digestion, and as a food emulsifier analog.
• Reference Standard: Employed as a certified reference material (CRM) for analytical method development and quality control in analytical laboratories.

Basic Information

Product Name	1,2-Distearoyl-Rac-Glycerol
CAS No.	1323-83-7
Molecular Formula	C39H76O5
Molecular Weight	625.02 g/mol
Synonyms	1,2-Di-O-stearoyl-rac-glycerol; rac-1,2-Distearoylglycerol; 1,2-Di-O-stearoyl-sn-glycerol; DAG(18:0/18:0); Diacylglycerol (18:0); 1,2-Distearin; Glycerol 1,2-distearate; Glyceryl 1,2-distearate
EINECS	215-350-6

Quality Control

Our 1,2-Distearoyl-Rac-Glycerol is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets stringent specifications for use in sensitive applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting critical quality attributes. We support compliance with cGMP, ICH Q7, and other relevant regulatory guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Avoid exposure to excessive heat and moisture. For long-term storage, consider inert gas (nitrogen) purging to minimize oxidation.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents	Complies with ICH Q3C
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.