Description

Palmitoylethanolamide CAS NO 544-31-0 is a naturally occurring fatty acid amide, recognized as a key endocannabinoid-like lipid mediator. This compound is of significant commercial interest for its role in modulating inflammatory and pain pathways through interaction with the endocannabinoid system. It is primarily sought by manufacturers in the nutraceutical, pharmaceutical, and cosmeceutical industries for developing advanced health and wellness products.

Application

• Nutraceutical Formulations: A core ingredient in dietary supplements targeting neuropathic pain, chronic inflammation, and immune system support.
• Pharmaceutical Intermediates: Used in the research and development of novel analgesic and anti-inflammatory drug candidates.
• Cosmeceutical Products: Incorporated into topical creams and serums for its purported skin-soothing and anti-irritant properties.
• Biomedical Research: Serves as a critical reference standard and biochemical tool for studying the endocannabinoid system and peroxisome proliferator-activated receptor-alpha (PPAR-α) pathways.
• Veterinary Supplements: Used in companion animal health products for managing discomfort and supporting joint health.

Basic Information

Product Name	Palmitoylethanolamide
CAS No.	544-31-0
Molecular Formula	C₁₈H₃₇NO₂
Molecular Weight	299.49 g/mol
Synonyms	N-(2-Hydroxyethyl)hexadecanamide; N-Palmitoylethanolamine; PEA; Palmidrol; N-(2-Hydroxyethyl)palmitamide; Hydroxyethylpalmitamide; N-Hexadecanoylethanolamine; Impulsin
EINECS	208-869-2

Quality Control

Our Palmitoylethanolamide is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, residual solvent analysis, and heavy metals screening, to ensure it meets stringent specifications for high-grade applications. Certificates of Analysis (COA) documenting identity, purity, and safety are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); the container must be kept tightly sealed after opening to prevent degradation due to moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Melting Point	98°C - 102°C
Loss on Drying	≤ 1.0%
Heavy Metals (as Pb)	≤ 10 ppm
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.