Description

3-(4-Fluoro-2-Methyl-Benzyl)-Piperidine is a high-purity, advanced pharmaceutical intermediate featuring a piperidine scaffold with a fluorinated benzyl substituent. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and receptor-targeted therapies. It is essential for research institutions and pharmaceutical manufacturers engaged in drug discovery and process development, where precise molecular architecture and reliable supply are paramount.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates targeting neurological and psychiatric disorders.
• Chemical Synthesis Building Block: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Research & Development: Employed in academic and industrial R&D labs for exploring new pharmacophores and biological pathways.
• Active Pharmaceutical Ingredient (API) Manufacturing: Serves as a critical raw material in the multi-step synthesis of final drug substances under GMP conditions.
• Ligand and Receptor Probe Development: Useful in creating specialized compounds for biochemical assays and diagnostic research.

Basic Information

Product Name	3-(4-Fluoro-2-Methyl-Benzyl)-Piperidine
CAS No.	955315-13-6
Molecular Formula	C13H18FN
Molecular Weight	207.29 g/mol
Synonyms	3-[(4-Fluoro-2-methylphenyl)methyl]piperidine; 1-(4-Fluoro-2-methylbenzyl)piperidin-3-amine (tautomer); 4-Fluoro-2-methylbenzylpiperidine; 955315-13-6; 3-(4-Fluoro-2-methyl-benzyl)-piperidine; Piperidine, 3-[(4-fluoro-2-methylphenyl)methyl]-; 3-(4-Fluoro-2-methylbenzyl)piperidine
EINECS	Contact for details

Quality Control

Our 3-(4-Fluoro-2-Methyl-Benzyl)-Piperidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications. Our quality commitment supports applications requiring high standards, including cGMP for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen) to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.