Description

trans-2-(4-n-Propylpiperazin-1-Yl)Cyclopentanamine is a specialized organic compound featuring a cyclopentylamine core substituted with a propylpiperazine moiety, serving as a key chiral intermediate in advanced pharmaceutical synthesis. This compound matters for its role in constructing complex molecular architectures, particularly for active pharmaceutical ingredients (APIs) targeting central nervous system (CNS) disorders. Pharmaceutical R&D departments and fine chemical manufacturers need this high-purity building block to develop new therapeutic agents and conduct process optimization.

Application

• Pharmaceutical Intermediate: A critical chiral building block in the synthesis of novel psychoactive pharmaceuticals and CNS-targeting drug candidates.
• Chemical Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization programs.
• Process Chemistry: Serves as a key starting material or advanced intermediate in the scale-up and commercial manufacturing of APIs.
• Reference Standard: Employed as an analytical standard for quality control and method development in pharmaceutical analysis.
• Asymmetric Synthesis: Utilized in catalytic asymmetric reactions to introduce stereochemical complexity into target molecules.

Basic Information

Product Name	trans-2-(4-n-Propylpiperazin-1-Yl)Cyclopentanamine
CAS No.	954566-63-3
Molecular Formula	C12H25N3
Molecular Weight	211.35 g/mol
Synonyms	trans-2-(4-Propylpiperazin-1-yl)cyclopentanamine; (1R,2S)-2-(4-Propylpiperazin-1-yl)cyclopentan-1-amine; (1S,2R)-2-(4-Propylpiperazin-1-yl)cyclopentan-1-amine; 2-(4-Propyl-1-piperazinyl)cyclopentanamine (trans); trans-2-(4-Propylpiperazino)cyclopentylamine; PC-amine intermediate; CAS 954566-63-3
EINECS	Contact for details

Quality Control

Our trans-2-(4-n-Propylpiperazin-1-Yl)Cyclopentanamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification and impurity profiling by HPLC, to ensure it meets the high standards required for pharmaceutical development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and specific tests is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.