Description

trans-2-(4-Acetylpiperazin-1-Yl)Cyclopentanamine is a high-purity, advanced pharmaceutical intermediate featuring a unique cyclopentylamine core linked to an acetylpiperazine moiety. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for constructing novel bioactive molecules. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and biotechnology sectors for the synthesis of potential drug candidates targeting central nervous system (CNS) disorders and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research-scale synthesis of novel active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Process Chemistry Development: Serves as a starting material or intermediate for developing scalable synthetic routes for new chemical entities (NCEs).
• CNS Drug Discovery: Particularly valuable for constructing molecules aimed at neurological targets, given its structural features.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and development services for the global pharmaceutical industry.
• Academic Research: Used in university and institutional labs for advanced organic synthesis and pharmacological studies.

Basic Information

Product Name	trans-2-(4-Acetylpiperazin-1-Yl)Cyclopentanamine
CAS No.	954251-72-0
Molecular Formula	C11H21N3O
Molecular Weight	211.31 g/mol
Synonyms	trans-2-(4-Acetyl-1-piperazinyl)cyclopentanamine; 1-[2-Amino-1-cyclopentyl]acetyl-4-piperazine; 2-(4-Acetylpiperazin-1-yl)cyclopentanamine (trans); Cyclopentanamine, 2-(4-acetyl-1-piperazinyl)-, trans-; 954251-72-0; trans-2-(4-Acetylpiperazinyl)cyclopentylamine; (1R,2S)- or (1S,2R)-2-(4-Acetylpiperazin-1-yl)cyclopentanamine
EINECS	Contact for details

Quality Control

Our trans-2-(4-Acetylpiperazin-1-Yl)Cyclopentanamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing identity, purity (by HPLC), chiral excess, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere after opening to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% de (trans isomer)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.