Description

1-Boc-4-(1-Oxo-Indan-5-Yl)-Piperazine is a high-purity, advanced pharmaceutical intermediate featuring a piperazine scaffold protected by a tert-butoxycarbonyl (Boc) group and linked to a 1-oxoindan moiety. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for the synthesis of novel bioactive molecules. It is primarily sought by pharmaceutical R&D teams and fine chemical manufacturers engaged in developing new therapeutic agents, particularly within central nervous system (CNS) and oncology drug discovery pipelines.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of potential drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used as a scaffold for structure-activity relationship (SAR) studies to optimize potency and selectivity of new chemical entities.
• Protease Inhibitor Development: The structural motifs present are relevant for the design of inhibitors for specific enzyme targets.
• Chemical Biology Probes: Utilized in the creation of molecular probes to study biological processes and identify new drug targets.
• Custom Synthesis Building Block: Supplied to contract research organizations (CROs) and CDMOs for custom synthesis projects.
• Library Synthesis for High-Throughput Screening: Employed in the generation of diverse compound libraries for biological screening.

Basic Information

Product Name	1-Boc-4-(1-Oxo-Indan-5-Yl)-Piperazine
CAS No.	954240-38-1
Molecular Formula	C18H24N2O3
Molecular Weight	316.40 g/mol
Synonyms	1-Boc-4-(1-oxo-2,3-dihydro-1H-inden-5-yl)piperazine; tert-Butyl 4-(1-oxo-2,3-dihydro-1H-inden-5-yl)piperazine-1-carboxylate; 5-(4-Boc-piperazin-1-yl)-indan-1-one; 1-Oxo-5-(4-Boc-piperazinyl)indane; N-Boc-4-(1-oxoindan-5-yl)piperazine; 1-(tert-Butoxycarbonyl)-4-(1-oxo-2,3-dihydro-1H-inden-5-yl)piperazine
EINECS	Contact for details

Quality Control

Our 1-Boc-4-(1-Oxo-Indan-5-Yl)-Piperazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.