Description

4-(4-Methylamino-Benzyl)-Piperazine-1-Carboxylic Acid tert-Butyl Ester is a high-purity, protected piperazine derivative that serves as a critical building block in advanced organic synthesis. This compound is valued for its role in constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the creation of novel pesticides and herbicides, leveraging its structural features to modulate biological activity.
• Ligand and Catalyst Development: Serves as a precursor for designing specialized ligands used in asymmetric catalysis and metal complexation.
• Peptidomimetic Chemistry: Employed in the synthesis of peptide analogs and mimetics due to the presence of the piperazine and protected carboxylic acid functionalities.
• Chemical Biology Probes: Utilized as a scaffold for developing molecular probes to study biological pathways and protein interactions.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis projects requiring specific, high-value nitrogen-containing heterocycles.

Basic Information

Product Name	4-(4-Methylamino-Benzyl)-Piperazine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	954240-26-7
Molecular Formula	C18H29N3O2
Molecular Weight	319.45 g/mol
Synonyms	tert-Butyl 4-[(4-(methylamino)phenyl)methyl]piperazine-1-carboxylate; 1-Boc-4-[(4-(methylamino)phenyl)methyl]piperazine; 4-[(4-(Methylamino)phenyl)methyl]-1-piperazinecarboxylic acid 1,1-dimethylethyl ester; 1-(tert-Butoxycarbonyl)-4-[4-(methylamino)benzyl]piperazine; N-Boc-4-(4-Methylaminobenzyl)piperazine; BOC-4-(4-Methylaminobenzyl)piperazine; 954240-26-7
EINECS	Contact for details

Quality Control

Our 4-(4-Methylamino-Benzyl)-Piperazine-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.