Description

tert-Butyl 4-((3-Trifluoromethylphenoxy)Methyl)Piperidine-1-Carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its piperidine core and trifluoromethylphenoxy moiety. This compound is of significant value in medicinal chemistry for its role as a versatile building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of central nervous system (CNS) agents, kinase inhibitors, and other therapeutic small molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly for CNS disorders and oncology.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies due to its modifiable functional groups.
• API Synthesis: Serves as a critical precursor in multi-step synthetic routes for complex target molecules.
• Chemical Biology Probes: Utilized in the development of tool compounds for studying biological pathways and target validation.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for client-specific projects.

Basic Information

Product Name	tert-Butyl 4-((3-Trifluoromethylphenoxy)Methyl)Piperidine-1-Carboxylate
CAS No.	954229-23-3
Molecular Formula	C18H24F3NO3
Molecular Weight	359.38 g/mol
Synonyms	1-Boc-4-[(3-(trifluoromethyl)phenoxy)methyl]piperidine; 4-[(3-(Trifluoromethyl)phenoxy)methyl]piperidine-1-carboxylic acid tert-butyl ester; tert-Butyl 4-[[[3-(trifluoromethyl)phenyl]oxy]methyl]-1-piperidinecarboxylate; 1-Piperidinecarboxylic acid, 4-[[[3-(trifluoromethyl)phenyl]oxy]methyl]-, 1,1-dimethylethyl ester; 954229-23-3; Boc-4-((3-trifluoromethylphenoxy)methyl)piperidine
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-((3-Trifluoromethylphenoxy)Methyl)Piperidine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.