Description

Tetradecanoic Acid 1,1′-[(1R)-1-[[[(2,3-Dihydroxypropoxy)Hydroxyphosphinyl]Oxy]Methyl]-1,2-Ethanediyl] Ester Monoammonium Salt is a specialized, high-purity synthetic phospholipid derivative. This compound is engineered for applications requiring precise molecular structure and consistent performance, offering a unique combination of a fatty acid ester and a phosphorylated glycerol backbone. It is primarily utilized in advanced pharmaceutical research and development, particularly in drug delivery systems and as a critical intermediate for novel therapeutic agents. The monoammonium salt form enhances its stability and solubility profile for formulation purposes.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of advanced lipid-based drug delivery systems, including liposomes and lipid nanoparticles (LNPs) for mRNA and other nucleic acid therapies.
• Excipient Development: Used in the research and formulation of novel phospholipid excipients to improve drug solubility, bioavailability, and targeted release.
• Biochemical Research: Serves as a critical reagent in membrane biology studies, model membrane formation, and investigating lipid-protein interactions.
• Cosmetic Actives Carrier: Explored in high-end cosmetic formulations for its potential to encapsulate and stabilize active ingredients for enhanced skin delivery.
• Diagnostic Agent Synthesis: Employed as a precursor in the development of contrast agents or probes for medical imaging techniques.

Basic Information

Product Name	Tetradecanoic Acid 1,1′-[(1R)-1-[[[(2,3-Dihydroxypropoxy)Hydroxyphosphinyl]Oxy]Methyl]-1,2-Ethanediyl] Ester Monoammonium Salt
CAS No.	953758-30-0
Molecular Formula	C19H41NO9P
Molecular Weight	458.50 g/mol
Synonyms	1,2-Ditetradecanoyl-rac-glycero-3-phosphate monoammonium salt; rac-1,2-Dimyristoylphosphatidic acid ammonium salt; DMPA ammonium salt; 1,2-Dimyristoyl-sn-glycero-3-phosphate (ammonium salt); Phosphatidic acid (myristoyl, ammonium salt); PA(14:0/14:0) ammonium salt; (R)-1,2-Bis(tetradecanoyloxy)-3-(phosphonooxy)propyl ammonium; rac-Glycerol-1,2-dimyristate-3-phosphate ammonium salt
EINECS	Contact for details

Quality Control

Our Tetradecanoic Acid 1,1′-[(1R)-1-[[[(2,3-Dihydroxypropoxy)Hydroxyphosphinyl]Oxy]Methyl]-1,2-Ethanediyl] Ester Monoammonium Salt is manufactured under strict quality management systems. Each batch is subjected to rigorous analytical testing, including HPLC for purity and assay, NMR and MS for structural confirmation, and specific tests for residual solvents and moisture. We provide comprehensive Certificates of Analysis (COA) to ensure traceability and compliance with your research or cGMP guidelines for pharmaceutical intermediates. Specifications can be customized to meet advanced project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. This product is hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere after each use to prevent degradation. Keep away from strong acids and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Purity (HPLC, Area%)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH limits
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.