Description

1-(4-Bromophenyl)-3-[4-(3-Chlorophenyl)Piperazino]-1-Propanone is a high-purity, advanced pharmaceutical intermediate featuring a distinct piperazine-linked aromatic ketone structure. This compound is valued for its role as a critical building block in the synthesis of novel bioactive molecules, particularly in central nervous system (CNS) and receptor-targeted therapeutic research. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers developing next-generation drug candidates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential antipsychotic and neuroleptic drug candidates targeting dopamine and serotonin receptors.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and the development of new chemical entities (NCEs).
• Biochemical Tool Compound: Used in vitro and in vivo to study receptor binding affinity, pharmacokinetics, and metabolic pathways.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up synthesis under cGMP conditions for clinical trial material production.
• Academic Research: Employed in university and institutional labs for foundational research in organic synthesis and pharmacology.

Basic Information

Product Name	1-(4-Bromophenyl)-3-[4-(3-Chlorophenyl)Piperazino]-1-Propanone
CAS No.	952182-60-4
Molecular Formula	C19H20BrClN2O
Molecular Weight	407.73 g/mol
Synonyms	1-(4-Bromophenyl)-3-[4-(3-chlorophenyl)-1-piperazinyl]-1-propanone; 3-[4-(3-Chlorophenyl)piperazin-1-yl]-1-(4-bromophenyl)propan-1-one; 1-Propanone, 1-(4-bromophenyl)-3-[4-(3-chlorophenyl)-1-piperazinyl]-; 952182-60-4; 4'-Bromo-3'-[4-(3-chlorophenyl)piperazin-1-yl]propiophenone
EINECS	Contact for details

Quality Control

Our 1-(4-Bromophenyl)-3-[4-(3-Chlorophenyl)Piperazino]-1-Propanone is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with each shipment, ensuring traceability and compliance with your research or development protocols. Specifications can be tailored to meet specific project requirements, including custom purity grades.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.