Description

5,6,7,8-Tetrahydro-3-Isopropyl-[1,2,4]Triazolo[4,3-A]Pyrazine is a high-purity, heterocyclic organic compound with the CAS number 952182-05-7, serving as a critical advanced pharmaceutical intermediate (API) and a versatile building block in medicinal chemistry. Its fused triazolopyrazine structure makes it a valuable scaffold for designing novel bioactive molecules, particularly in the development of central nervous system (CNS) and metabolic disorder therapeutics. This compound is essential for research and development laboratories, pharmaceutical manufacturers, and fine chemical synthesis companies seeking to innovate in drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly for neurological and psychiatric targets.
• Medicinal Chemistry Research: Used as a privileged scaffold in high-throughput screening and structure-activity relationship (SAR) studies.
• Active Pharmaceutical Ingredient (API) Synthesis: Incorporated into the final chemical structure of investigational and approved therapeutic agents.
• Fine Chemical Manufacturing: Serves as a precursor for the production of more complex, high-value specialty chemicals.
• Contract Research & Development (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the life sciences industry.
• Academic Research: Utilized in university and institutional labs for fundamental studies in organic synthesis and heterocyclic chemistry.

Basic Information

Item	Detail
Product Name	5,6,7,8-Tetrahydro-3-Isopropyl-[1,2,4]Triazolo[4,3-A]Pyrazine
CAS No.	952182-05-7
Molecular Formula	C8H14N4
Molecular Weight	166.23 g/mol
Synonyms	3-Isopropyl-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine; 3-(Propan-2-yl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine; Tetrahydro-3-isopropyl-[1,2,4]triazolo[4,3-a]pyrazine; 952182-05-7; 3-Isopropyl-5,6,7,8-tetrahydro-1,2,4-triazolo[4,3-a]pyrazine
EINECS	Contact for details

Quality Control

Every batch of 5,6,7,8-Tetrahydro-3-Isopropyl-[1,2,4]Triazolo[4,3-A]Pyrazine is manufactured under a strict quality management system and undergoes comprehensive analytical testing. We ensure compliance with ICH guidelines for impurities and provide full traceability. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and conformance to agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5% Total impurities ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤ 0.5% w/w
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.