Description

1-Piperazinecarboxylic Acid, 4-(3,4-Difluorophenyl)-, 1,1-Dimethylethyl Ester is a high-value, protected piperazine derivative serving as a critical synthetic intermediate in modern organic chemistry. Its core value lies in providing a versatile, functionalized scaffold for constructing complex molecules, particularly in regulated industries where purity and structural precision are paramount. This compound is essential for research and development chemists and process engineers in the pharmaceutical and agrochemical sectors, where it is used to develop new active ingredients.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and psychiatric disorder treatments.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides and fungicides, leveraging the difluorophenyl moiety for enhanced biological activity.
• Chemical Biology & Proteomics: Serves as a precursor for designing enzyme inhibitors, receptor ligands, and other molecular probes for biological target validation.
• Material Science Research: Employed in the development of specialty polymers and advanced organic materials with specific electronic or structural properties.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	1-Piperazinecarboxylic Acid, 4-(3,4-Difluorophenyl)-, 1,1-Dimethylethyl Ester
CAS No.	951626-88-3
Molecular Formula	C15H20F2N2O2
Molecular Weight	298.33 g/mol
Synonyms	tert-Butyl 4-(3,4-difluorophenyl)piperazine-1-carboxylate; 4-(3,4-Difluorophenyl)-1-piperazinecarboxylic acid 1,1-dimethylethyl ester; 1-Boc-4-(3,4-difluorophenyl)piperazine; N-Boc-4-(3,4-difluorophenyl)piperazine; Boc-3,4-difluorophenylpiperazine; 951626-88-3; 4-(3,4-Difluorophenyl)piperazine-1-carboxylic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our production of 1-Piperazinecarboxylic Acid, 4-(3,4-Difluorophenyl)-, 1,1-Dimethylethyl Ester adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment. Our quality systems are designed to support development through to commercial scale, meeting the rigorous standards expected in pharmaceutical ingredient supply chains.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.