Description

tert-Butyl 4-(3-Fluorophenyl)Piperazine-1-Carboxylate is a high-purity, protected piperazine derivative of significant importance in modern organic synthesis. This compound serves as a versatile and critical building block for the development of novel pharmaceutical agents and advanced materials. It is primarily sought after by research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used extensively in hit-to-lead optimization and structure-activity relationship (SAR) studies for new drug candidates.
• Agrochemical Development: Serves as a building block for creating novel fungicides, herbicides, and insecticides with enhanced efficacy.
• Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up processes under cGMP conditions.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying biological pathways and protein interactions.

Basic Information

Product Name	tert-Butyl 4-(3-Fluorophenyl)Piperazine-1-Carboxylate
CAS No.	951626-85-0
Molecular Formula	C15H21FN2O2
Molecular Weight	280.34 g/mol
Synonyms	1-Boc-4-(3-fluorophenyl)piperazine; tert-Butyl 4-(3-fluorophenyl)-1-piperazinecarboxylate; 4-(3-Fluorophenyl)-1-piperazinecarboxylic acid tert-butyl ester; 1-(tert-Butoxycarbonyl)-4-(3-fluorophenyl)piperazine; 3-Fluorophenylpiperazine-1-carboxylic acid tert-butyl ester; N-Boc-3-fluorophenylpiperazine; Boc-3-FPP; 951626-85-0
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-(3-Fluorophenyl)Piperazine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports applications from research to commercial-scale cGMP production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to prevent moisture absorption and contamination. For long-term storage, consider inert gas purging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.