Description

(2E)-N-[2-[2-(1-Methyl-2-Piperidinyl)Ethyl]Phenyl]-3-Phenyl-2-Propenamide is a specialized organic compound featuring a complex molecular architecture that combines a propenamide core with phenyl and piperidinyl substituents. This structure makes it a valuable intermediate in advanced pharmaceutical research and development, particularly for creating novel therapeutic agents. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and fine chemical industries for synthesizing potential drug candidates targeting neurological and other disorders.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) targets.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to develop new drug candidates with optimized potency and selectivity.
• Process Chemistry Development: Serves as a critical intermediate for scaling up synthetic routes from laboratory to pilot plant scale.
• Reference Standard: Employed as an analytical standard for quality control and method validation in API manufacturing.
• Biochemical Probe Development: Utilized in research to create tools for studying specific biological pathways and receptor interactions.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs producing bespoke compounds for client projects.

Basic Information

Product Name	(2E)-N-[2-[2-(1-Methyl-2-Piperidinyl)Ethyl]Phenyl]-3-Phenyl-2-Propenamide
CAS No.	951155-18-3
Molecular Formula	C23H28N2O
Molecular Weight	348.49 g/mol
Synonyms	(E)-N-[2-[2-(1-Methylpiperidin-2-yl)ethyl]phenyl]-3-phenylprop-2-enamide; (2E)-N-[2-[2-(1-Methyl-2-piperidinyl)ethyl]phenyl]-3-phenyl-2-propenamide; 951155-18-3; trans-N-[2-[2-(1-Methyl-2-piperidinyl)ethyl]phenyl]cinnamamide; (E)-Cinnamamido Derivative of 1-Methyl-2-(2-phenylethyl)piperidine; UNII-Contact for details; Propenamide derivative CAS 951155-18-3
EINECS	Contact for details

Quality Control

Our production of (2E)-N-[2-[2-(1-Methyl-2-Piperidinyl)Ethyl]Phenyl]-3-Phenyl-2-Propenamide adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with each shipment, ensuring traceability and compliance with your research or cGMP guidelines for advanced intermediates. Our quality system is designed to meet the exacting standards of the global pharmaceutical supply chain.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.