Description

n-(5-Bromopyrazin-2-Yl)-2-Amino-4-Methoxyaniline is a high-purity, advanced pharmaceutical intermediate characterized by its bromopyrazine and substituted aniline structure. This compound matters for its critical role as a versatile building block in the synthesis of complex, biologically active molecules, enabling precise molecular modifications. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating new drug candidates and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and antiviral drug discovery programs.
• Agrochemical Research: Used in the development of new herbicides and fungicides, leveraging its heterocyclic structure for bioactivity.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the creation of specialized polymers and organic electronic materials.
• Chemical Synthesis Reagent: Employed in cross-coupling reactions (e.g., Buchwald-Hartwig amination, Suzuki reactions) to introduce complex amine and heterocyclic motifs.
• Dye and Pigment Intermediate: Utilized in the production of specialized dyes and pigments due to its conjugated aniline-pyrazine system.
• Academic & Contract Research: Essential for medicinal chemistry research in academic institutions and contract research organizations (CROs).

Basic Information

Item	Detail
Product Name	n-(5-Bromopyrazin-2-Yl)-2-Amino-4-Methoxyaniline
CAS No.	950845-96-2
Molecular Formula	C11H11BrN4O
Molecular Weight	295.14 g/mol
Synonyms	2-Methoxy-5-[(5-bromopyrazin-2-yl)amino]aniline; 4-Methoxy-2-[(5-bromopyrazin-2-yl)amino]aniline; 1-(5-Bromopyrazin-2-yl)-2-amino-4-methoxybenzene; 5-Bromo-N-(2-amino-4-methoxyphenyl)pyrazin-2-amine; Benzenamine, 2-methoxy-5-[(5-bromopyrazin-2-yl)amino]-; 950845-96-2; 5-Bromo-2-[(2-amino-4-methoxyphenyl)amino]pyrazine
EINECS	Contact for details

Quality Control

Our n-(5-Bromopyrazin-2-Yl)-2-Amino-4-Methoxyaniline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting full specifications are available upon request, supporting compliance in GMP and ISO 9001 environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This material is light-sensitive (store away from light). Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Light yellow to brown powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.