Description

tert-Butyl 4-[(5-Methyl-2-Nitrophenyl)Amino]-Piperidine-1-Carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its piperidine and aromatic nitroamine structure. This compound is critical for research and development in medicinal chemistry, serving as a versatile building block for synthesizing novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing new therapeutic agents, particularly in areas requiring complex heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes in drug discovery pipelines.
• API Synthesis: Serves as a precursor in multi-step synthetic routes for complex molecules in pre-clinical and clinical development.
• Chemical Reference Standard: Employed as an analytical standard for quality control and method development in pharmaceutical analysis.
• Academic & Industrial R&D: Facilitates novel organic synthesis methodologies and exploration of new chemical entities in university and corporate research settings.

Basic Information

Product Name	tert-Butyl 4-[(5-Methyl-2-Nitrophenyl)Amino]-Piperidine-1-Carboxylate
CAS No.	950772-97-1
Molecular Formula	C17H25N3O4
Molecular Weight	335.40 g/mol
Synonyms	1-Boc-4-[(5-Methyl-2-nitrophenyl)amino]piperidine; tert-Butyl 4-((5-methyl-2-nitrophenyl)amino)piperidine-1-carboxylate; 4-[(5-Methyl-2-nitrophenyl)amino]-1-piperidinecarboxylic acid 1,1-dimethylethyl ester; 1,1-Dimethylethyl 4-[(5-methyl-2-nitrophenyl)amino]-1-piperidinecarboxylate; N-(5-Methyl-2-nitrophenyl)-4-(Boc-amino)piperidine; BOC-4-[(5-Methyl-2-nitroanilino)]piperidine; 950772-97-1; UNII-Contact for details
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-[(5-Methyl-2-Nitrophenyl)Amino]-Piperidine-1-Carboxylate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. All products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. Certificates of Analysis (COA) with detailed specifications are provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.