Description

3-(4-Piperidinyloxy)Benzonitrile Hydrochloride is a high-purity, non-racemic organic building block of significant interest in advanced chemical synthesis. This compound is valued for its role as a key chiral intermediate in the development of novel active pharmaceutical ingredients (APIs). It is primarily sought after by research and development teams within the pharmaceutical and biotechnology sectors for the synthesis of complex, biologically active molecules.

Application

• Pharmaceutical Intermediate: A critical chiral building block in the research and development of new drug candidates, particularly for central nervous system (CNS) and other therapeutic areas.
• Chemical Synthesis: Used in advanced organic synthesis for constructing complex molecular architectures containing piperidine and benzonitrile motifs.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Process Chemistry: Employed in the scale-up and optimization of synthetic routes for target molecules during clinical development phases.
• Reference Standard: Can be utilized as a high-purity analytical standard for method development and quality control in API manufacturing.

Basic Information

Product Name	3-(4-Piperidinyloxy)Benzonitrile Hydrochloride
CAS No.	950649-07-7
Molecular Formula	C₁₂H₁₅ClN₂O
Molecular Weight	238.71 g/mol
Synonyms	3-[(4-Piperidinyl)oxy]benzonitrile hydrochloride; 3-(Piperidin-4-yloxy)benzonitrile HCl; Benzonitrile, 3-[(4-piperidinyl)oxy]-, hydrochloride; 4-(3-Cyanophenoxy)piperidine hydrochloride; 3-(4-Piperidyloxy)benzonitrile hydrochloride; (RS)-3-(Piperidin-4-yloxy)benzonitrile hydrochloride
EINECS	Contact for details

Quality Control

Our 3-(4-Piperidinyloxy)Benzonitrile Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) providing identity, purity, and impurity profile is supplied with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.