Description

tert-Butyl 4-(3-Cyanophenoxy)Piperidine-1-Carboxylate is a high-purity, advanced pharmaceutical intermediate of significant commercial interest. This compound serves as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), enabling the development of new therapeutic agents. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly in central nervous system (CNS) and oncology research pipelines.
• Organic Synthesis Building Block: Used in medicinal chemistry for constructing piperidine-based scaffolds and introducing functionalized phenoxy groups.
• Research & Development (R&D): Essential for academic and industrial laboratories exploring new chemical entities and structure-activity relationships (SAR).
• Process Chemistry: Employed in the scale-up and optimization of synthetic routes for candidate drugs during pre-clinical and clinical development stages.
• Custom Synthesis: Serves as a starting material for the contract manufacturing of specialized, non-commercial compounds for client-specific projects.

Basic Information

Product Name	tert-Butyl 4-(3-Cyanophenoxy)Piperidine-1-Carboxylate
CAS No.	950649-06-6
Molecular Formula	C17H22N2O3
Molecular Weight	302.37 g/mol
Synonyms	1-Boc-4-(3-cyanophenoxy)piperidine; 4-(3-Cyanophenoxy)piperidine-1-carboxylic acid tert-butyl ester; tert-Butyl 4-(3-cyanophenoxy)-1-piperidinecarboxylate; 1-(tert-Butoxycarbonyl)-4-(3-cyanophenoxy)piperidine; 950649-06-6; 4-(3-Cyanophenoxy)-1-piperidinecarboxylic acid 1,1-dimethylethyl ester; Boc-4-(3-cyanophenoxy)piperidine
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-(3-Cyanophenoxy)Piperidine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee compliance with your research and production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.