Description

1-tert-Butyl 4-Methyl 4-(Iodomethyl)Piperidine-1,4-Dicarboxylate is a versatile and highly functionalized piperidine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the strategic placement of reactive functional groups—the iodomethyl moiety and the carboxylate esters—which enable precise molecular construction. This compound is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries, where it is used to create complex molecules with specific biological activities.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral drug candidates.
• Agrochemical Synthesis: Building block for creating advanced herbicides, fungicides, and insecticides with tailored efficacy and environmental profiles.
• Ligand and Catalyst Development: Used in the synthesis of complex nitrogen-containing ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Enables the synthesis of labeled compounds and molecular probes for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: A high-value starting material for custom synthesis projects and scale-up processes under cGMP or ISO standards.
• Academic & Industrial R&D: Fundamental research tool in medicinal chemistry and process chemistry for exploring new synthetic methodologies.

Basic Information

Product Name	1-tert-Butyl 4-Methyl 4-(Iodomethyl)Piperidine-1,4-Dicarboxylate
CAS No.	948895-07-6
Molecular Formula	C13H22INO4
Molecular Weight	383.22 g/mol
Synonyms	4-(Iodomethyl)-1-(tert-butoxycarbonyl)-4-(methoxycarbonyl)piperidine; tert-Butyl 4-(iodomethyl)-4-(methoxycarbonyl)piperidine-1-carboxylate; 1-Boc-4-(iodomethyl)-4-(methyl carboxylate)piperidine; 4-(Iodomethyl)-1-Boc-4-piperidinecarboxylic acid methyl ester; Piperidine-1,4-dicarboxylic acid, 4-(iodomethyl)-, 1-(1,1-dimethylethyl) 4-methyl ester
EINECS	Contact for details

Quality Control

Our 1-tert-Butyl 4-Methyl 4-(Iodomethyl)Piperidine-1,4-Dicarboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production can align with cGMP guidelines for pharmaceutical applications upon request, ensuring supply chain reliability and regulatory compliance for global markets.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability. Keep the container tightly sealed when not in use to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.