Description

Butanedioic Acid, 2,3-Bis(Benzoyloxy)-, (2S,3S)-, Compd. With Ethyl (3Ar,6Ar)-Hexahydropyrrolo[3,4-B]Pyrrole-5(1H)-Carboxylate (1:) is a high-purity, stereochemically defined organic salt with significant utility in advanced pharmaceutical synthesis. This compound matters as a critical chiral building block or intermediate for the development of complex active pharmaceutical ingredients (APIs), particularly those targeting the central nervous system. It is primarily needed by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in process chemistry and the production of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the multi-step synthesis of complex drug molecules, especially in neurological and psychiatric drug discovery.
• Asymmetric Synthesis: Used in catalytic or stoichiometric reactions to induce or control stereoselectivity in the formation of new carbon-heteroatom bonds.
• Process Chemistry Development: Employed in route scouting and optimization for the scalable manufacturing of target APIs under Good Manufacturing Practice (GMP) conditions.
• Research & Development: Utilized in academic and industrial research for exploring new chemical entities and biological activities.
• Reference Standard: Can be supplied as a high-purity standard for analytical method development, validation, and quality control testing.

Basic Information

Item	Details
Product Name	Butanedioic Acid, 2,3-Bis(Benzoyloxy)-, (2S,3S)-, Compd. With Ethyl (3Ar,6Ar)-Hexahydropyrrolo[3,4-B]Pyrrole-5(1H)-Carboxylate (1:)
CAS No.	948846-40-0
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	(2S,3S)-2,3-Bis(benzoyloxy)succinic acid compound with ethyl hexahydropyrrolo[3,4-b]pyrrole-5(1H)-carboxylate (1:1); Ethyl octahydro-2H-pyrrolo[3,4-b]pyrrole-5-carboxylate (2S,3S)-2,3-bis(benzoyloxy)succinate; Succinic acid, 2,3-bis(benzoyloxy)-, (2S,3S)-, compd. with ethyl hexahydropyrrolo[3,4-b]pyrrole-5-carboxylate (1:1); A pharmaceutical salt intermediate of a DPP-4 inhibitor precursor.
EINECS	Contact for details

Quality Control

Our Butanedioic Acid, 2,3-Bis(Benzoyloxy)-, (2S,3S)-, Compd. With Ethyl (3Ar,6Ar)-Hexahydropyrrolo[3,4-B]Pyrrole-5(1H)-Carboxylate (1:) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing including chiral purity assay and impurity profiling to ensure it meets the stringent requirements for pharmaceutical development. Certificates of Analysis (COA) detailing identity, purity, and related substances are available upon request, supporting compliance with ICH guidelines and customer-specific specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, the container must be kept tightly sealed under controlled humidity conditions to prevent moisture absorption. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.