Description

(R)-6-Benzyl-Piperazin-2-One is a high-purity chiral piperazinone derivative, a key building block in advanced pharmaceutical synthesis. Its defined stereochemistry and functionalized core make it an invaluable intermediate for developing novel active pharmaceutical ingredients (APIs). This compound is primarily utilized by research institutions and manufacturers in the pharmaceutical and biotechnology sectors for the synthesis of complex, biologically active molecules.

Application

• Pharmaceutical Intermediate: A critical chiral synthon in the research and development of new therapeutic agents, particularly in central nervous system (CNS) and oncology drug candidates.
• Asymmetric Synthesis: Serves as a versatile scaffold for constructing complex molecular architectures requiring high enantiomeric purity.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs to explore new chemical entities.
• Process Chemistry Development: Employed in scaling up synthetic routes for potential APIs during clinical trial material and commercial manufacturing stages.
• Reference Standard: Can be used as a high-purity analytical standard for method development and quality control in pharmaceutical analysis.

Basic Information

Product Name	(R)-6-Benzyl-Piperazin-2-One
CAS No.	947685-07-6
Molecular Formula	C11H14N2O
Molecular Weight	190.24 g/mol
Synonyms	(R)-6-Benzylpiperazin-2-one; (R)-6-Benzyl-2-piperazinone; (R)-1-Benzyl-3-oxopiperazine; (R)-6-Phenylmethyl-2-piperazinone; (R)-2-Piperazinone, 6-benzyl-; (R)-6-Benzyl-1,4-diazinan-2-one; (R)-6-Benzyl-3,4,5,6-tetrahydropyrazin-2(1H)-one
EINECS	Contact for details

Quality Control

Our (R)-6-Benzyl-Piperazin-2-One is manufactured under strict quality management systems to ensure batch-to-batch consistency and high chemical purity. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity (by HPLC), chiral purity, and impurity profiles. We adhere to cGMP guidelines for the production of pharmaceutical intermediates, ensuring traceability and documentation for regulatory compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.