Description

(R)-1-Boc-2-Benzylpiperazine CAS NO 947684-78-8 is a high-purity, chiral piperazine derivative that serves as a critical building block in advanced organic synthesis. Its value lies in providing a protected, enantiomerically pure scaffold essential for constructing complex molecules with defined stereochemistry. This compound is primarily needed by pharmaceutical R&D and fine chemical manufacturers for applications in drug discovery, particularly in the development of active pharmaceutical ingredients (APIs) and chiral ligands.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of novel drug candidates, especially for central nervous system (CNS) and oncology targets.
• Asymmetric Catalyst Ligand Precursor: Used to develop chiral ligands for metal-catalyzed asymmetric reactions, enhancing enantioselectivity.
• Peptidomimetic Chemistry: Incorporated into peptide backbones to create stable, bioactive peptidomimetics with improved pharmacological properties.
• Chemical Biology Probes: Serves as a core structure for designing molecular probes to study enzyme function and receptor interactions.
• Agrochemical Research: Employed in the discovery of new chiral active ingredients for crop protection.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic and medicinal chemistry laboratories worldwide.

Basic Information

Product Name	(R)-1-Boc-2-Benzylpiperazine
CAS No.	947684-78-8
Molecular Formula	C16H24N2O2
Molecular Weight	276.38 g/mol
Synonyms	(R)-1-(tert-Butoxycarbonyl)-2-benzylpiperazine; (R)-N-Boc-2-Benzylpiperazine; (R)-2-Benzyl-1-Boc-piperazine; (R)-1-Boc-2-(Phenylmethyl)piperazine; tert-Butyl (R)-2-benzylpiperazine-1-carboxylate; (R)-1-Boc-2-Bn-piperazine; (R)-2-Benzylpiperazine-1-carboxylic acid tert-butyl ester; (R)-1-(tert-Butyloxycarbonyl)-2-benzylpiperazine
EINECS	Contact for details

Quality Control

Our (R)-1-Boc-2-Benzylpiperazine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high enantiomeric purity. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, chiral purity, and impurity profiles. We adhere to cGMP standards where applicable, ensuring the material is suitable for demanding research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.