Description

(S)-3-Benzyl-1-(2-Methoxy-Benzenesulfonyl)-Piperazine Hydrochloride is a high-purity, chiral piperazine derivative used as a critical synthetic intermediate in advanced pharmaceutical research and development. This compound matters for its role in constructing complex molecular architectures, particularly in the synthesis of potential therapeutic agents targeting the central nervous system. Pharmaceutical companies and advanced research laboratories need this building block for developing novel drug candidates, especially in areas requiring enantiomerically pure intermediates.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) targets.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for drug discovery programs.
• Asymmetric Synthesis: Serves as a chiral scaffold or auxiliary in the preparation of enantiomerically pure compounds for biological evaluation.
• Chemical Reference Standard: Employed as a high-purity standard for analytical method development and validation in quality control laboratories.
• Process Chemistry Development: Used in scaling up synthetic routes from laboratory to pilot plant scale for new drug candidates.
• Academic Research: A valuable reagent for universities and research institutes studying novel synthetic methodologies and heterocyclic chemistry.

Basic Information

Product Name	(S)-3-Benzyl-1-(2-Methoxy-Benzenesulfonyl)-Piperazine Hydrochloride
CAS No.	947532-50-5
Molecular Formula	C18H22N2O3S • HCl
Molecular Weight	394.91 g/mol
Synonyms	(S)-1-(2-Methoxybenzenesulfonyl)-3-benzylpiperazine hydrochloride; (S)-3-Benzyl-1-(2-methoxyphenylsulfonyl)piperazine HCl; (S)-3-Benzyl-1-(o-anisylsulfonyl)piperazine hydrochloride; (S)-1-(2-Methoxybenzenesulfonyl)-3-(phenylmethyl)piperazine hydrochloride; (S)-3-Benzyl-1-(2-methoxybenzenesulfonyl)piperazine monohydrochloride; (S)-3-Benzyl-1-(2-methoxybenzenesulfonyl)piperazine HCl salt; (S)-3-Benzyl-1-(2-methoxy-phenylsulfonyl)-piperazine hydrochloride
EINECS	Contact for details

Quality Control

Our (S)-3-Benzyl-1-(2-Methoxy-Benzenesulfonyl)-Piperazine Hydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to confirm identity and meet stringent specifications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key parameters such as assay, enantiomeric excess, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to prevent moisture absorption, which may affect stability and performance. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.