Description

(S)-3-Isopropyl-1-(2-Methoxy-Benzenesulfonyl)-Piperazine Hydrochloride is a high-purity chiral sulfonamide building block essential for advanced pharmaceutical research and development. This compound serves as a critical intermediate in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders. It is primarily utilized by medicinal chemists and process development scientists in pharmaceutical and biotechnology companies for drug discovery programs and route scouting.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of potential drug candidates, especially in neuroscience and psychiatry.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its defined stereochemistry and functional groups.
• Process Chemistry Development: Serves as a starting material or advanced intermediate for scaling up synthetic routes under Good Manufacturing Practice (GMP) conditions.
• Reference Standard: Employed as an analytical standard for method development and quality control of complex synthetic pathways.
• Chemical Biology Probes: Utilized in the development of tool compounds for studying biological pathways and target validation.

Basic Information

Product Name	(S)-3-Isopropyl-1-(2-Methoxy-Benzenesulfonyl)-Piperazine Hydrochloride
CAS No.	947532-48-1
Molecular Formula	C15H25ClN2O3S
Molecular Weight	348.89 g/mol
Synonyms	(S)-1-(2-Methoxybenzenesulfonyl)-3-(propan-2-yl)piperazine hydrochloride; (S)-3-Isopropyl-1-(2-methoxyphenylsulfonyl)piperazine HCl; (S)-1-(o-Anisylsulfonyl)-3-isopropylpiperazine hydrochloride; (S)-3-(1-Methylethyl)-1-[(2-methoxyphenyl)sulfonyl]piperazine hydrochloride; (S)-1-(2-Methoxybenzenesulfonyl)-3-isopropylpiperazine hydrochloride; Piperazine, 1-[(2-methoxyphenyl)sulfonyl]-3-(1-methylethyl)-, hydrochloride, (3S)-; 947532-48-1
EINECS	Contact for details

Quality Control

Our (S)-3-Isopropyl-1-(2-Methoxy-Benzenesulfonyl)-Piperazine Hydrochloride is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity (HPLC), chiral purity, and impurity profiles. We adhere to relevant industry guidelines to support our customers' regulatory and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.