Description

(S)-1-Boc-4-Benzylpiperazine-2-Carbaldehyde is a high-purity chiral building block and advanced pharmaceutical intermediate. This compound is of significant value for its role in the synthesis of complex molecules, particularly in medicinal chemistry and drug discovery. It is primarily needed by research institutions and pharmaceutical companies developing active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic agents, including potential central nervous system (CNS) drugs and enzyme inhibitors.
• Asymmetric Synthesis: Utilized as a versatile building block for constructing complex, enantiomerically pure molecules due to its aldehyde and protected amine functionalities.
• Medicinal Chemistry Research: Serves as a critical scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Peptidomimetic Synthesis: Used in the design and synthesis of peptidomimetics and other bioactive compounds that mimic peptide structures.
• Custom Synthesis & Contract Manufacturing: An essential starting material for custom synthesis services and contract research organizations (CROs/CMOs) producing specialized fine chemicals.

Basic Information

Product Name	(S)-1-Boc-4-Benzylpiperazine-2-Carbaldehyde
CAS No.	947275-36-7
Molecular Formula	C17H24N2O3
Molecular Weight	304.39 g/mol
Synonyms	(S)-1-(tert-Butoxycarbonyl)-4-benzylpiperazine-2-carboxaldehyde; (S)-1-Boc-4-benzyl-2-piperazinecarboxaldehyde; (S)-tert-Butyl 4-benzyl-2-formylpiperazine-1-carboxylate; (S)-1-Boc-4-Bn-piperazine-2-carbaldehyde; (S)-N-Boc-4-benzylpiperazine-2-carbaldehyde; 1-Piperazinecarboxaldehyde, 1-(1,1-dimethylethoxy)carbonyl-4-(phenylmethyl)-, (2S)-; (2S)-1-[(2-Methylpropan-2-yl)oxycarbonyl]-4-benzylpiperazine-2-carbaldehyde
EINECS	Contact for details

Quality Control

Our (S)-1-Boc-4-Benzylpiperazine-2-Carbaldehyde is manufactured under strict quality control protocols to ensure high chemical purity and chiral integrity, suitable for demanding research and development applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, chiral purity (enantiomeric excess), and impurity profiles. We adhere to cGMP principles where applicable to support pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label or COA. This material is easily oxidized (store under inert atmosphere) and light-sensitive (store away from light). Keep container tightly sealed under an inert atmosphere (nitrogen or argon) to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% e.e.
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.