Description

(R)-1-Boc-3-Benzylpiperazine is a high-purity, chiral piperazine derivative of significant importance in advanced organic synthesis. This compound serves as a critical chiral building block and intermediate for the development of active pharmaceutical ingredients (APIs) and other fine chemicals. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel, stereospecific molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic agents, particularly for central nervous system (CNS) drugs and receptor modulators.
• Asymmetric Synthesis: Used as a chiral auxiliary or ligand precursor in catalytic asymmetric reactions to induce stereoselectivity.
• Peptidomimetics & Drug Discovery: Incorporated into the backbone of peptidomimetic compounds to enhance metabolic stability and binding affinity.
• Agrochemical Research: Serves as a building block for developing new chiral pesticides and herbicides with improved efficacy and environmental profiles.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes for studying enzyme mechanisms and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high stereochemical purity.

Basic Information

Product Name	(R)-1-Boc-3-Benzylpiperazine
CAS No.	947272-49-3
Molecular Formula	C16H24N2O2
Molecular Weight	276.38 g/mol
Synonyms	(R)-1-(tert-Butoxycarbonyl)-3-benzylpiperazine; (R)-3-Benzyl-1-Boc-piperazine; (R)-N-Boc-3-benzylpiperazine; (R)-1-Boc-3-(phenylmethyl)piperazine; tert-Butyl (R)-3-benzylpiperazine-1-carboxylate; (R)-1-Boc-3-Bn-piperazine; (R)-3-Benzylpiperazine-1-carboxylic acid tert-butyl ester; (R)-1-N-Boc-3-benzylpiperazine
EINECS	Contact for details

Quality Control

Our (R)-1-Boc-3-Benzylpiperazine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric excess (ee) and standard purity assays, to ensure it meets the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability, consistency, and compliance with your project specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.