Description

Benzyl 4-Hydroxy-4-(Trifluoromethyl)Piperidine-1-Carboxylate is a high-value, multi-functional piperidine derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring a hydroxyl group and a trifluoromethyl moiety on the piperidine ring, makes it an essential intermediate for creating novel compounds with enhanced biological activity and physicochemical properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in central nervous system (CNS) and metabolic disease research.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethyl group can improve efficacy and environmental profile.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of novel polymers and advanced materials with specific functional properties.
• Chemical Biology Probes: Utilized to build molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Item	Details
Product Name	Benzyl 4-Hydroxy-4-(Trifluoromethyl)Piperidine-1-Carboxylate
CAS No.	946504-83-2
Molecular Formula	C14H16F3NO3
Molecular Weight	303.28 g/mol
Synonyms	1-CBz-4-Hydroxy-4-(trifluoromethyl)piperidine; Benzyl 4-Hydroxy-4-(trifluoromethyl)piperidine-1-carboxylate; 4-(Trifluoromethyl)-4-hydroxypiperidine-1-carboxylic acid benzyl ester; 1-Benzyloxycarbonyl-4-hydroxy-4-trifluoromethylpiperidine; N-CBz-4-Hydroxy-4-trifluoromethylpiperidine; 4-Hydroxy-4-(trifluoromethyl)piperidine-1-carboxylic Acid Benzyl Ester; 1,4-Piperidinedicarboxylic acid, 4-hydroxy-4-(trifluoromethyl)-, 1-benzyl ester
EINECS	Contact for details

Quality Control

Our Benzyl 4-Hydroxy-4-(Trifluoromethyl)Piperidine-1-Carboxylate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical quality attributes. We adhere to cGMP principles where applicable to support our clients' regulatory and research needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect product stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.