Description

1-(4-Fluoro-2-(Trifluoromethyl)Phenyl)-3-Methylpiperazine is a high-value, multi-functional fluorinated piperazine derivative used as a critical building block in advanced organic synthesis. Its unique structure, featuring both fluorine and trifluoromethyl groups, makes it an essential intermediate for developing novel compounds with enhanced biological activity and physicochemical properties. This compound is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for creating new active ingredients and fine-tuning molecular properties.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) agents, anti-infectives, and oncology therapeutics.
• Agrochemical Synthesis: Used in the creation of novel pesticides and herbicides, where the fluorine atoms can improve metabolic stability and membrane permeability.
• Material Science Research: Serves as a precursor for specialty chemicals and advanced materials, including liquid crystals and polymers with specific electronic properties.
• Chemical Biology Probe Development: Employed in the design of molecular probes and tool compounds for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules.

Basic Information

Product Name	1-(4-Fluoro-2-(Trifluoromethyl)Phenyl)-3-Methylpiperazine
CAS No.	946399-84-4
Molecular Formula	C12H12F4N2
Molecular Weight	260.23 g/mol
Synonyms	3-Methyl-1-[4-fluoro-2-(trifluoromethyl)phenyl]piperazine; 1-(4-Fluoro-2-(trifluoromethyl)phenyl)-3-methylpiperazine; 4-Fluoro-2-(trifluoromethyl)phenyl-3-methylpiperazine; 946399-84-4; 3-Methyl-1-(4-fluoro-α,α,α-trifluoro-o-tolyl)piperazine
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for our fine chemical intermediates. Each batch of 1-(4-Fluoro-2-(Trifluoromethyl)Phenyl)-3-Methylpiperazine is analyzed using advanced techniques like HPLC, GC, and NMR to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment. Our quality system is designed to support cGMP-compliant applications and meet the exacting standards of global pharmaceutical and agrochemical partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, open flames, and incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Individual impurity ≤ 1.0%
Total Impurities	≤ 3.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.