Description

5-[3-[2-[[4'-(Cyclohexylmethoxy)[1,1'-Biphenyl]-4-Yl]Methyl]-4-(2,4-Dichlorophenyl)-1H-Imidazol-1-Yl]Phenyl]-1,2,5-Thiadiazolidin-3-One 1,1-Dioxide is a high-purity, non-peptidic small molecule compound designed for advanced pharmaceutical research and development. This compound serves as a critical intermediate or active pharmaceutical ingredient (API) in the synthesis pathway for novel therapeutic agents. It is primarily utilized by pharmaceutical companies, biotechnology firms, and contract research organizations (CROs) engaged in drug discovery programs targeting complex diseases.

Application

• Pharmaceutical Intermediate: Key building block in the multi-step synthesis of investigational new drugs.
• Drug Discovery Research: Used as a reference standard or a core scaffold in medicinal chemistry for structure-activity relationship (SAR) studies.
• Biochemical Assay Development: Employed as a tool compound in high-throughput screening (HTS) to identify and validate novel biological targets.
• Preclinical Studies: Sourced for formulation development and pharmacokinetic/pharmacodynamic (PK/PD) evaluation in animal models.
• Process Chemistry: Used for scaling up and optimizing synthetic routes under Good Manufacturing Practice (GMP) conditions for clinical trial material production.

Basic Information

Item	Detail
Product Name	5-[3-[2-[[4'-(Cyclohexylmethoxy)[1,1'-Biphenyl]-4-Yl]Methyl]-4-(2,4-Dichlorophenyl)-1H-Imidazol-1-Yl]Phenyl]-1,2,5-Thiadiazolidin-3-One 1,1-Dioxide
CAS No.	945836-48-6
Molecular Formula	C38H36Cl2N4O4S
Molecular Weight	715.69 g/mol
Synonyms	TAK-715; TAK715; TAK 715; 1,2,5-Thiadiazolidin-3-one 1,1-dioxide, 5-[3-[2-[[4'-(cyclohexylmethoxy)[1,1'-biphenyl]-4-yl]methyl]-4-(2,4-dichlorophenyl)-1H-imidazol-1-yl]phenyl]-; Biphenylimidazole thiadiazolidinedioxide; p38 MAP kinase inhibitor TAK-715; UNII-6J8X4H2I6F
EINECS	Contact for details

Quality Control

Our pharmaceutical-grade material is produced under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis, to ensure it meets the stringent requirements for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. This compound is light-sensitive (store away from light) and hygroscopic (moisture-sensitive). For long-term storage, consider desiccation and an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Retention time corresponds to reference standard
Identification (NMR)	Spectrum consistent with reference structure
Purity (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.