Description

tert-Butyl-4-(2-Fluorophenoxy)Piperidine-1-Carboxylate is a high-value, advanced pharmaceutical intermediate characterized by its piperidine core and fluorinated phenoxy substituent. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing new therapeutic agents, particularly in the areas of central nervous system (CNS) and cardiovascular drug discovery.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new drug candidates.
• Medicinal Chemistry Building Block: Used for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• API Synthesis: Employed in the multi-step synthesis of complex active pharmaceutical ingredients, particularly those targeting neurological receptors.
• Chemical Biology Research: Serves as a probe or ligand in biochemical assays and target validation studies.
• Process Chemistry Development: Used for scaling up synthetic routes from laboratory to pilot plant scale.
• Custom Synthesis: A starting material for the contract manufacturing of specialized fine chemicals and proprietary compounds.

Basic Information

Product Name	tert-Butyl-4-(2-Fluorophenoxy)Piperidine-1-Carboxylate
CAS No.	944808-08-6
Molecular Formula	C16H22FNO3
Molecular Weight	295.35 g/mol
Synonyms	1-Boc-4-(2-Fluorophenoxy)piperidine; 4-(2-Fluorophenoxy)piperidine-1-carboxylic acid tert-butyl ester; tert-Butyl 4-(2-fluorophenoxy)-1-piperidinecarboxylate; 1-(tert-Butoxycarbonyl)-4-(2-fluorophenoxy)piperidine; N-Boc-4-(2-fluorophenoxy)piperidine; BOC-4-(2-Fluorophenoxy)piperidine; 944808-08-6; UNII-7K9J8VU2VH
EINECS	Contact for details

Quality Control

Our tert-Butyl-4-(2-Fluorophenoxy)Piperidine-1-Carboxylate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot is analyzed using advanced chromatographic and spectroscopic techniques (HPLC, GC, NMR, MS) to confirm identity, purity, and impurity profile. Certificates of Analysis (COA) detailing all test results are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container sealed to protect this moisture-sensitive compound from humidity. Store away from incompatible materials such as strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.