Description

2-Pyrazinecarbonitrile, 3-Amino-5-(1-Methylethyl)- is a high-purity, functionalized heterocyclic building block of significant interest in advanced organic synthesis. Its value lies in the strategic combination of an amino group and a nitrile functionality on the pyrazine core, enabling its use as a versatile precursor for complex molecular architectures. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized chelating ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as components for OLEDs or conductive polymers.
• Chemical Biology Probes: Utilized to build molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis and Contract Manufacturing: A critical building block for custom synthesis projects requiring specific, multi-functional heterocycles.

Basic Information

Product Name	2-Pyrazinecarbonitrile, 3-Amino-5-(1-Methylethyl)-
CAS No.	944506-59-6
Molecular Formula	C8H10N4
Molecular Weight	162.19 g/mol
Synonyms	3-Amino-5-isopropylpyrazine-2-carbonitrile; 5-Isopropyl-3-aminopyrazine-2-carbonitrile; 3-Amino-5-(propan-2-yl)pyrazine-2-carbonitrile; 2-Cyano-3-amino-5-isopropylpyrazine; 3-Amino-5-(1-methylethyl)-2-pyrazinecarbonitrile; Isopropylaminopyrazinecarbonitrile
EINECS	Contact for details

Quality Control

Our 2-Pyrazinecarbonitrile, 3-Amino-5-(1-Methylethyl)- is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with full traceability are provided for every shipment, supporting compliance in GMP-aligned applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.